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Joe O’Brien, a 44-year-old police officer from Boston, is a devoted husband and father of four. His life is turned upside down when he begins experiencing uncharacteristic temper outbursts, strange movements, and memory lapses. A devastating diagnosis follows: Huntington’s disease, a fatal neurodegenerative disorder with no cure. As Joe struggles with the impact of his illness, his family must confront the possibility that they, too, may inherit the disease. Inside the O’Briens is a powerful and moving story about resilience, love, and the choices we make when faced with unimaginable challenges. Lisa Genova, bestselling author of Still Alice, delivers another deeply human, emotionally rich novel that sheds light on an often misunderstood condition.